Triple Mix (or Triple Drug or Trimix):
Triple Mix Injection (alprostadil, phentolamine, and papaverine) is injected into a specific area of the penis (see injection instructions) and should produce an erection in 5 to 20 minutes. The erection can be expected to last up to one hour. You should not use Triple Mix Injection more than 3 times a week. Injections should be administered at least 24 hours apart.
Ideally, the injection should be administered just prior to foreplay. If your partner experiences insufficient vaginal lubrication or painful vaginal sensations during intercourse, the use of a lubricant may be helpful.
Who should NOT use Triple Mix Injection? Men who have conditions that might result in long-lasting erections should not use Triple Mix Injection. Some of these conditions include sickle cell anemia or trait, leukemia, and tumor of the bone marrow (multiple myeloma). If you have any of these conditions, consult your doctor. Men with penile implants, severe penile curvature, or those who have been advised not to engage in sexual activity should not use Triple Mix Injection. Triple Mix Injection should not be used by women or children.
What are the risks of using Triple Mix Injection? Erections that last more than 6 hours can cause serious damage to the penile tissue and may result in permanent impotence. Call the prescribing physician or, if unavailable, seek professional help immediately if you still have an erection 4 hours after injection. Various treatment options for reversing a prolonged erection are available, including pseudoephridene (many doctors instruct their patients how to use this rescue treatment in teh event of an erection that does not go away.
A common side effect of Triple Mix Injection is mild to moderate pain during injection. The erection may also be associated with a painful sensation. If you experience severe pain, contact the prescribing physician. Call your doctor if you notice any redness, lumps, swelling, tenderness or curvature of the erect penis.
A small amount of bleeding at the injection site may occur. To prevent bruising, apply firm pressure to the injection site for 5 minutes after injecting. Tell your doctor if you have a condition or are taking a medicine that interferes with blood clotting.
NOTE: There is a sleight possibility of needle breakage with use of Triple Mix Injection. To best avoid breaking the needle, pay careful attention to your doctor’s instructions and handle syringe and needle properly. If the needle breaks during injection and you are able to see and grasp the broken end, you should remove it and contact your doctor. If you cannot see or cannot grasp the broken end, you should promptly contact your doctor.
Storage: Store in the refrigerator. Keep out of the reach of children and pets. Store all medicines away from excess heat and moisture. Do NOT store in the bathroom.