What Is It?: Clomipramine is one of the tricyclic antidepressants. It is used for a wide variety of conditions, including depression, obsessive-compulsive disorder and pain.

How To Use: Clomipramine is taken by mouth. It usually is taken one to three times a day with meals or once a day at bedtime. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take clomipramine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Continue to take clomipramine even if you feel well. Do not stop taking clomipramine without talking to your doctor, especially if you have taken large doses for a long time. Your doctor probably will decrease your dose gradually. This drug must be taken regularly for a few weeks before its full effect is felt.

Possible Side Effects: Clomipramine may cause an upset stomach. Take clomipramine with food or milk. Although side effects from clomipramine are not common, they can occur. Tell your doctor if any of these symptoms are severe or do not go away: drowsiness, dry mouth, upset stomach, vomiting, diarrhea, constipation, nervousness, decreased sexual ability, decreased memory or concentration, headache, stuffy nose, change in appetite or weight.

If you experience any of the following symptoms or those listed in the IMPORTANT WARNING section, call your doctor immediately: tremor, seizures, fast, irregular, or pounding heartbeat, difficulty urinating or loss of bladder control, depression, delusions or hallucinations, eye pain, shakiness, difficulty breathing or fast breathing, severe muscle stiffness, unusual tiredness or weakness

Storage: Keep in the original container. Keep out of the reach of children and pets. Capsules and tablets may be stored at room temperature. Some liquids should be stored in the refrigerator (see the prescription label.)  Store all medicines away from excess heat and moisture. Do NOT store in the bathroom.

Note: If you miss a dose take it as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not take a double dose to make up for the missed one.