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NALTREXONE STABILITY IN WATER
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Formulation and stability of naltrexone oral liquid for rapid withdrawal from methadone
JP Fawcett, NC Morgan, and DJ Woods

OBJECTIVE: To assess the stability of naltrexone oral liquid prepared from tablets and powder, ....

DESIGN: Naltrexone 1 mg/mL oral liquids were prepared from tablets and powder and stored in the dark at 4, 25, and 70 degrees C.

SETTING: A university pharmacy school and affiliated urban teaching hospital.

CONCLUSIONS: Naltrexone 1 mg/mL oral liquids prepared from tablets or powder  are stable when stored in the dark for 60 days at 4 degrees C and for 30 days at 25 degrees C.
 

  

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The formulation prepared from tablets provides flexible dosing in patients undergoing rapid withdrawal from methadone.

The Annals of Pharmacotherapy: Vol. 31, No. 11, pp. 1291-1295.
Harvey Whitney Books Company.

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